个人基本信息
姓名:马振玲
性别:女
职称:副教授
邮编:450046
通讯地址:河南省郑州市金水区文化路95号 河南农业大学生命科学学院
E-mail:xmzl@henau.eud.cn
个人简介
2018.10-至今 河南农业大学 遗传与细胞生物学系 讲师/副教授;2014.09-2018.06 厦门大学 生命科学学院 细胞生物学专业 博士学位;
2011.09-2014.06 新乡医学院 生命科学学院 细胞生物学专业 硕士学位。
教授课程
细胞生物学、细胞工程、细胞生物学研究专题
主要研究领域
中药单体抗炎、抗肿瘤机制研究
发表论著
1. Ma Z, Zhang J, Li Z, Zhu Y, Han X, Lei L, Cheng K, Liu W. Interleukin-1b inhibits ovarian cancer cell proliferation and metastasis through the MAPK/MMP12 pathway. Int J Mol Sci. 2025, 26(7): 3287.
2. Ma Z, Han X, Zhu Y, Fu P, Li Z, Zhao Y, Yang J, Liu W. Expression and purification of human stem cell factor and its effect on the growth of A549 cells. Protein journal. 2025, 44(4): 377-386.
3. Liu W, Yuan C, Fu B, Xie J, Li W, Zhang G, Ma Z, Jiao P. E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS. Cell reports. 2024, 43(9): 114687.
4. Ma Z, Wang L, Cheng K, Xing G, Zhang J, Liu W. RNA sequencing of A2780 cells treated with CCL2 identified genes associated with A2780 cell growth. Current Proteomics. 2023, 20(2): 128-135.
5. Liu W, Wang L, Zhang J, Cheng K, Zheng W, Ma Z. CC-chemokine 2 promotes ovarian cancer progression through the MEK/ERK/MAP3K19 signaling pathway. Int J Mol Sci. 2023, 24(13): 10652.
6. Zhang J, Liu W, Xing G, Xiang L, Zheng W, Ma Z. Role of CC-chemokine 2 in gynecological cancer. Cancer Cell Int. 2022, 22(1):361.
7. Ma Z, Zhang W, Fan W, Wu Y, Zhang M, Xu J, Liu W, Sun L, Liu W, Liu W. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses. Int Immunopharmacol. 2021, 90: 107152.
8. Ma Z, Zhang W, Wu Y, Zhang M, Wang L, Wang Y, Wang Y, Liu W. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway. Biosci Rep. 2021, 41(1): BSR20203219.
9. Ma Z, Zhang J, Wang L, Liu Y, Wang Y, Liu W, Xing G, Cheng K, Zheng W, Xiang L. Expression and purifcation of recombinant human CCL5 and its biological characterization. Protein J. 2022, 41(2): 337-344.
10. Zhang J, Wang L, Liu Y, Liu W, Ma Z. Exogenous interleukin-1 beta promotes the proliferation and migration of HeLa cells via the MEK/ERK signaling pathway. Mol Biol Rep. 2022, 49(5): 3765-3772.
11. Liu W, Wang L, Zhang J, Qiao L, Liu Y, Yang X, Zhang J, Zheng W, Ma Z. Purifcation of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer. 3 Biotech. 2021, 11(1): 8.
12. Ma Z, Zhao X, Deng M, Huang Z, Wang J, Wu Y, Cui D, Liu Y, Liu R, Ouyang G. Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-cell Acute Lymphoblastic Leukemia Progression by Modulating CCL2 in Leukemia Cells. Cell Reports. 2019, 26(6):1533-1543.
13. Ma Z, Zhao X, Huang J, Jia X, Deng M, Cui D, Du Z, Fu G, Ouyang G, Xiao C. A critical role of periostin in B-cell acute lymphoblastic leukemia. Leukemia. 2017, 31(8):1835-1837.
14. 马振玲,王雷,乔柳惠,刘薇. 小鼠CCL2 蛋白原核表达及纯化分析. 生物学杂志,2021, 38(06):20-24.
1. 河南省高等学校重点科研项目,主持,2025.01-2026.122. Ma Z, Han X, Zhu Y, Fu P, Li Z, Zhao Y, Yang J, Liu W. Expression and purification of human stem cell factor and its effect on the growth of A549 cells. Protein journal. 2025, 44(4): 377-386.
3. Liu W, Yuan C, Fu B, Xie J, Li W, Zhang G, Ma Z, Jiao P. E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS. Cell reports. 2024, 43(9): 114687.
4. Ma Z, Wang L, Cheng K, Xing G, Zhang J, Liu W. RNA sequencing of A2780 cells treated with CCL2 identified genes associated with A2780 cell growth. Current Proteomics. 2023, 20(2): 128-135.
5. Liu W, Wang L, Zhang J, Cheng K, Zheng W, Ma Z. CC-chemokine 2 promotes ovarian cancer progression through the MEK/ERK/MAP3K19 signaling pathway. Int J Mol Sci. 2023, 24(13): 10652.
6. Zhang J, Liu W, Xing G, Xiang L, Zheng W, Ma Z. Role of CC-chemokine 2 in gynecological cancer. Cancer Cell Int. 2022, 22(1):361.
7. Ma Z, Zhang W, Fan W, Wu Y, Zhang M, Xu J, Liu W, Sun L, Liu W, Liu W. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses. Int Immunopharmacol. 2021, 90: 107152.
8. Ma Z, Zhang W, Wu Y, Zhang M, Wang L, Wang Y, Wang Y, Liu W. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway. Biosci Rep. 2021, 41(1): BSR20203219.
9. Ma Z, Zhang J, Wang L, Liu Y, Wang Y, Liu W, Xing G, Cheng K, Zheng W, Xiang L. Expression and purifcation of recombinant human CCL5 and its biological characterization. Protein J. 2022, 41(2): 337-344.
10. Zhang J, Wang L, Liu Y, Liu W, Ma Z. Exogenous interleukin-1 beta promotes the proliferation and migration of HeLa cells via the MEK/ERK signaling pathway. Mol Biol Rep. 2022, 49(5): 3765-3772.
11. Liu W, Wang L, Zhang J, Qiao L, Liu Y, Yang X, Zhang J, Zheng W, Ma Z. Purifcation of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer. 3 Biotech. 2021, 11(1): 8.
12. Ma Z, Zhao X, Deng M, Huang Z, Wang J, Wu Y, Cui D, Liu Y, Liu R, Ouyang G. Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-cell Acute Lymphoblastic Leukemia Progression by Modulating CCL2 in Leukemia Cells. Cell Reports. 2019, 26(6):1533-1543.
13. Ma Z, Zhao X, Huang J, Jia X, Deng M, Cui D, Du Z, Fu G, Ouyang G, Xiao C. A critical role of periostin in B-cell acute lymphoblastic leukemia. Leukemia. 2017, 31(8):1835-1837.
14. 马振玲,王雷,乔柳惠,刘薇. 小鼠CCL2 蛋白原核表达及纯化分析. 生物学杂志,2021, 38(06):20-24.
科研成果
2. 河南省研究生精品在线课程,主持,2024.1-2025.12
3. 河南省自然科学基金,主持,2022.01-2024.7
4. 河南省科技公关项目,主持,2020.01-2022.12
5. 河南省高等学校重点科研项目,主持,2022.1-2024.1
6. 授权国家发明专利:ZL 2022 1 1189306.7,2023.7.11,第一发明人
7. 授权国家发明专利:ZL 2021 1 0063433.1,2022.3.15,第一发明人
8. 授权国家发明专利:ZL 2021 1 0064938.X,2022.4.29,第一发明人
9. 授权国家发明专利:ZL 2022 1 1189300.X,2023.7.11,第二发明人